Bogdan Iorga Home Page

Scientific fields of interests:

  •  Biotechnology of contractile subcellular systems:

- Kinetic studies of molecular motors (myosin class II, actin-myosin complex);

- Characterization of the micromechanical properties of cellular and subcellular contractile systems isolated from different genetically controlled models: engineered heart tissues (EHT), cardiomyocytes differentiated from induced pluripotent stem cells (iPS cells);

- Kinetic studies of myofibrils isolated from different native (rabbit, guinea-pig, human) or genetically modified organisms (GMO: mice, zebrafish, flies);

- Micromechanical analysis of the low sinusoidal perturbation applied to skeletal and cardiac myofibrils.

 

  • Biophysics, Physiology and Pathophysiology of striated contractile systems:

- Functional characterization of cardiac muscles containing cardiomyopathy associated mutations in sarcomeric proteins;

- Functional and biochemical investigations of myofibrils isolated from the right ventricle of the myocardium of the patients with the Tetralogy of Fallot;

- Functional role of the Z-disc in mechanotransduction and in myofibrillogenesis.

 

 

 

 

 

 

 

Contact

Address: University of Bucharest, Faculty of Chemistry, Department of Physical Chemistry
Tel: +40 213 143 508 / ext. 2163
Fax: +40 213 159 249
Email: iorgabogdan@yahoo.com

member of:
Physical chemistry.

department of:
Faculty of Chemistry.

Curriculum Vitae

File type .pdf ! IORGA_BOGDAN, PhD

Lectures

 

Online Resources

 




Last updated at: March 07, 2011.