Prof. Dr. Abil. Anisoara Cimpean

Domenii de interes: Culturi celulare, Biomateriale si biocompatibilitate, Inginerie tisulara, Celule stem și medicina regenerativa, Biochimie clinica, Biologie celulara

Teza de abilitare: Dezvoltarea de strategii pentru evaluarea in vitro a unor noi biomateriale Fisier de tip .pdf ! Abilitare rezumat_Cimpean 

Carti, monografii, cursuri

1. Cimpean, A., Ion, R., Ciofrangeanu, C., Mitran, V., Galateanu, B., Iordachescu, D., Ghid practic de evaluare in vitro a biocompatibilitătii implanturilor dentare, 2008, Editura Ars Docendi, 118 p., ISBN: 978-973-558-364-4.

2. Cimpean, A., Culturi de celule animale, 2006, Editura Ars Docendi, 214 p., ISBN-10 973-558-274-0; ISBN-13 978-973-558-274-6.

3. Iordachescu, D., Cimpean, A., Stan, C., 2004, Modelarea matricei extracelulare. Aplicatii in ingineria tisulara, Editura Pro-Transilvania, 245 p., ISBN 973-715-024-4.

4. Gavrila, M., Cimpean, A., Metoda de izolare și cultivare a celulelor stem mezenchimale umane, 2007, 71 p., Editura Curtea Veche, ISBN 978-973-9467-92-6.

Capitole carti

1. Cimpean, A., Ion, R., Gordin D.-M., Neacsu, P., Mitran, V., Gloriant, T., Biomaterials as modulators of macrophage inflammatory response, Biomaterials (vol. 11) in: J.N. Govil (Ed.), Nanotechnology series, Studium Press LLC (USA), 139-176 (2013).

2. Dimonie D, Petrache M, Doncea S, Gabor R, Vasile E, Cimpean A, Fierascu RC, Cristian N, Dinescu S, Trandafir I, Anton L, Fierascu I, Galateanu B. 2013. New approaches to develop 3D layer shaped scaffolds for soft tissue engineering, In: Advanced biocompatible structures for prospective bioengineering: Concepts and strategies, Editura Academiei Române, p. 74-124, ISBN: 978-973-27-2317-3.

 

Articole publicate în reviste indexate ISI (selectiv)

Neacsu P, Staras AI, Voicu SI, Ionascu I, Soare T, Uzun S, Cojocaru VD, Pandele AM, Croitoru SM, Miculescu F, Cotrut CM, Dan I, Cimpean A. Characterization and In vitro and In vivo Assessment of a Novel Cellulose Acetate-coated Mg-based Alloy for Orthopaedic Applications, Materials, 2017, 10 (7), 686 (2017) http://www.mdpi.com/1996-1944/10/7/686/htm

Voicu SI, Condruz RM, Mitran V, Cimpean A, Miculescu F, Andronescu C, Miculescu M, Thakur VK. Sericin Covalent Immobilization onto Cellulose Acetate Membrane for Potential Osseointegration Applications. ACS Sustainable Chem Eng, 4, 1765-1774 (2016). http://pubs.acs.org/doi/abs/10.1021/acssuschemeng.5b01756

Ion R, Luculescu C, Cimpean A, Marx P, Gordin D-M, Gloriant T. Nitride coating enhances endothelialization on biomedical NiTi shape memory alloy. Mater Sci Eng C, 62, 686–691 (2016). http://www.sciencedirect.com/science/article/pii/S0928493116301217

Castany P, Gordin D-M, Drob SI, Vasilescu C, Mitran V, Cimpean A, Gloriant T. Deformation mechanisms and biocompatibility of the superelastic Ti–23Nb–0.7Ta–2Zr–0.5N alloy. Shap Mem Superelasticity, 2, 18-28 (2016). http://link.springer.com/article/10.1007/s40830-016-0057-0

Rusen L, Neacsu P, Cimpean A, Ion V, Brajnicova S, Dumitrescu LN, Banita J, Dinca V, Dinescu M. In vitro evaluation of poly(ethyleneglycol)-block-poly(e-caprolactone) methyl ether copolymer coating effects on cells adhesion and proliferation. Appl Surf Sci, 374, 23-30 (2016). http://www.sciencedirect.com/science/article/pii/S0169433215020383

Ion R, Stoian AB, Dumitriu C, Grigorescu S, Mazare A, Cimpean A, Demetrescu I, Schmuki P. Nanochannels formed on TiZr alloy improve biological response. Acta Biomater, 24, 270-377 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26092351

Neacsu P, Mazare A, Schmuki P, Cimpean A. Attenuation of the macrophage inflammatory activity by TiOnanotubes via inhibition of MAPK and NF-kB pathways. Int J Nanomedicine, 10, 6455-6476 (2015).        http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608594/

Mitran V, Vasilescu C, Drob SI, Osiceanu P, Calderon Moreno JM, Tabirca MC, Gordin DM, Gloriant T, Cimpean A. Biological behaviour and enhanced anticorrosive performance of the nitrided superelastic Ti-23Nb-0.7Ta-2Zr-0.5N alloy. BioMed Res Int, 125, article ID  261802 (2015). http://sci-hub.cc/10.1155/2015/261802

Drob SI, Vasilescu C, Calderon Moreno JM, Osiceanu P, Neacsu P, Cimpean A, Gordin DM, Gloriant T. Multifunctional "gum metal" titanium-based alloy: Its long-term electrochemical behaviour and macrophage response. Int J Electrochem Sci, 10, 10738-10755 (2015). http://www.electrochemsci.org/papers/vol10/101210738.pdf

Mitran V, Albu MG, Vasile E, Cimpean A, Costache M. Dose-related effects of sericin on preadipocyte behavior within collagen/sericin hybrid scaffolds. Prog Nat Sci Mater Internat, 25, 122-130 (2015). http://authors.elsevier.com/a/1R5SJ3Zr7s9kfE (free access) 

Neacsu P, Ion RN, Mitran V, Staras AI, Cimpean A. State of the art and recent patents on Mg-based biodegradable bone implants. Rec. Pat. Regen. Med., Vol. 4, Nr. 3, 168-188 (2015). DOI: 10.2174/2210296505666150205155811

Ion R, Vizireanu S, Stancu CE, Luculescu C, Cimpean A, Dinescu Gh. Surface plasma functionalization influences macrophage behavior on carbon nanowalls, Mater Sci Eng C Mater Biol Appl, 48, 118-125 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25579904

Neacsu P, Gordin DM, Mitran V, Gloriant T, Costache M, Cimpean A. In vitro performance assessment of new beta Ti-Mo-Nb alloy compositions, Mater Sci Eng C Mater Biol Applic, 47, 105-113 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25492178

Neacsu P, Mazare A, Cimpean A, Park J, Costache M, Schmuki P, Demetrescu I. Reduced inflammatory activity of RAW 264.7 macrophages on titania nanotube modified Ti surface, Int J Biochem Cell Biol, 55, 187-195 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25220343

Cimpean A, Vasilescu E, Drob P, Cinca I, Vasilescu C, Anastasescu M, Mitran V, Drob SI. Enhancement of the electrochemical behaviour and biological performance of Ti–25Ta–5Zr alloy by thermo-mechanical processing, Mater Sci Eng C Mater Biol Applic, 38, 127-142 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24656361

Cimpean A, Recent advances and challenges in adipose tissue engineering: Adipose derived stem cell-based approaches, Curr Tiss Eng, 3, 7-24 (2014). http://benthamscience.com/journal/abstracts.php?journalID=cte&articleID=119438

Ion R, Gordin DM, Mitran V, Osiceanu P, Dinescu S, Gloriant T, Cimpean A, In vitro biocompatibility performances of the novel superelastic beta-type Ti-23Nb-0.7Ta-2Zr-0.5N alloy, Mater Sci Eng C Mater Biol Applic, 35, 411-419 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24411395

Ion R, Vasilescu C, Drob P, Vasilescu E, Cimpean A, Drob I, Gordin DM, Gloriant T. Long-term corrosion performances and cytocompatibility of nitrided Ti and Ti–6Al–4V alloy in severe functional conditions, Mater Corros, 65, 593-604 (2014). http://onlinelibrary.wiley.com/doi/10.1002/maco.201206724/abstract

Mindroiu M, Ion R, Pirvu C, Cimpean A, Surfactant-dependent macrophage response to polypyrrole-based coatings electrodeposited on Ti6Al7Nb alloy, Mater Sci Eng C Mater Biol Applic, 33, 3353-3361 (2013).
http://www.sciencedirect.com/science/article/pii/S0928493113002300

Andronescu E, Ficai A, Albu M, Mitran V, Sonmez M, Ficai D, Ion R, Cimpean A. Collagen-hydroxyapatite/Cisplatin Drug Delivery Systems for Locoregional Treatment of Bone Cancer, Technol Cancer Res Treat, 12, 275-284 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23547973

Gordin DM, Gloriant T, Chane-Pane V, Busardo D, Mitran V, Hoche D, Vasilescu C, Drob SI, Cimpean A. Surface characterization and biocompatibility of titanium alloys implanted with nitrogen by Hardion+ technology, J Mater Sci: Mater Med, 23, 2953-2966 (2012).
http://www.ncbi.nlm.nih.gov/pubmed/22918550

Cimpean A, Mitran V, Ciofrangeanu CM, Galateanu B, Bertrand E, Gordin D-M, Iordachescu D, Gloriant T. Osteoblast cell behavior on the new beta-type Ti–25Ta–25Nb alloy, Mater Sci Eng C Mater Biol Applic, 32, 1554–1563 (2012).
http://www.sciencedirect.com/science/article/pii/S0928493112001610

Galateanu B., Dimonie D., Vasile E., Nae S., Cimpean A., Costache M., Layer-shaped Alginate Hydrogels Enhance the Biological Performance of Human Adipose-Derived Stem Cells, BMC Biotechnol 12, 35, http://www.biomedcentral.com/1472-6750/12/35 (2012). http://www.biomedcentral.com/1472-6750/12/35

Galateanu B., Dinescu S., Cimpean A, Dinischiotu A, Costache M., Modulation of adipogenic conditions for prospective use of hADSCs in adipose tissue engineering, Int J Mol Sci, 13, 15881-15900, doi:10.3390/ijms130x000x (2012).
http://www.ncbi.nlm.nih.gov/pubmed/23443100

Dinescu S., Galateanu B., Albu M., Cimpean A., Dinischiotu A., Costache M., Sericin Enhances the Bioperformance of Collagen-Based Matrices Preseeded with Human-Adipose Derived Stem Cells (hADSCs), Int J Mol Sci, 14, 1870-1889; doi:10.3390/ijms14011870 (2013).
http://www.mdpi.com/1422-0067/14/1/1870

Vasilescu C, Calderon Moreno JM, Cimpean A, Cojocaru D, Cinca I, Andronescu E, Grigore F, Galateanu B, Drob SI, Synthesis, mechanical and structural properties and biological activity of some nanostructured bone scaffolds, Digest J Nanomat Biostr, 6, 523-534 (2011). http://connection.ebscohost.com/c/articles/74592904/synthesis-mechanical-structural-properties-biological-activity-some-nanostructured-bone-scaffolds


Cimpean A, Popescu S, Ciofrangeanu CM, Gleizes AN. Effects of LP-MOCVD prepared TiO2 thin films on the in vitro behavior of gingival fibroblasts, Mat Chem Phys, 125, 485-492 (2011).
http://www.sciencedirect.com/science/article/pii/S025405841000859X

Raducanu D, Cimpean A, Vasilescu E, Cojocaru VD, Cinca I, Drob P, Ivanescu S. Corrosion behaviour and biocompatibility of a new dental noble AuPdAgTi alloy, Mater Corros, 61, 775-782 (2010). http://onlinelibrary.wiley.com/doi/10.1002/maco.201005636/abstract

Scorei RI, Ciofrangeanu C, Ion R, Cimpean A, Galateanu B, Mitran V, Iordachescu D. In Vitro Effects of Calcium Fructoborate upon Production of Inflammatory Mediators by LPS-stimulated RAW 264.7 Macrophages, Biol Trace Elem Res,135, 334-344 (2010).
http://www.ncbi.nlm.nih.gov/pubmed/19669712
 
Scorei R, Ciubar R, Ciofrangeanu CM, Mitran V, Cimpean A, Iordachescu D. Comparative effects of boric acid and calcium fructoborate on breast cancer cells, Biol Trace Elem Res, 122, 197-205 (2008).
http://www.ncbi.nlm.nih.gov/pubmed/18176783

Popa MV, Demetrescu I, Iordachescu D, Cimpean A, Vasilescu E, Drob P, Vasilescu C, Istratescu M, The relation between electrochemical tests and in vitro evaluation of titanium alloy biocompatibility, Mater Corros, 58, 667-675 (2007).
http://onlinelibrary.wiley.com/doi/10.1002/maco.200704053/abstract

Ciubar R, Ciofrangeanu C, Mitran V, Cimpean A, Stanescu A, Iordachescu D, The effect of lead ions on human erythrocytes in vitro, Rev Chim - Bucharest, 9, 895-808 (2007).
http://revistadechimie.ro/pdf/CIUBAR%20R..pdf

Scorei R, Ciubar R, Iancu C, Mitran V, Cimpean A, Iordachescu D, In vitro effects of calcium fructoborate on fMLP-stimulated human neutrophils granulocytes, Biol Trace Elem Res, 118, 27-37 (2007).
http://link.springer.com/article/10.1007%2Fs12011-007-0019-7#page-1

Ciubar R, Mitran V, Cimpean A, Iordachescu D, In vitro effects of nickel on human embrionary lung fibroblasts, Rev Roum Chim, 51, 199-203, 2006.
http://revroum.getion.ro/wp-content/uploads/2006/RRC_3_2006/Art.%2006.pdf

Cimpean A, Stefan C, Gijsbers R, Stalmans W, Bollen M, Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2, Biochem J, 381, 71-77 (2004).
http://www.ncbi.nlm.nih.gov/pubmed/15096095

 

 

 

 

 

Contact

Adresa: Splaiul Independentei 91-95, Sector 5, cod 050095, Bucuresti
Tel/Fax: +40 021 3181575 (106/102)
Email: anisoara.cimpean@bio.unibuc.ro
web: www.bio.unibuc.ro

Curriculum Vitae

Fisier de tip .pdf ! CV_Anisoara Cimpean

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Pagină actualizată la 29 Septembrie 2017.